Endocrine Abstracts

Background: Recent reports have mentioned rising incidence of thyroid cancer (TC) detected before and after thyroidec-tomy (Tx) for hyperthyroidism but “hyperfunctioning” TC is however a rare entity.Patients & Methods: Among a personal series of 464 patients which underwent Tx including 147 (33.6%) cases of thyroto-xicosis and 72 (13.6%) cases of TC, we founded 10 patients with hyperthyroidism and nodular or microscopic TC but only one case...

Introduction: Immunologic background often present different association of two or more autoimmune diseases. However the coexistence of Basedow disease (BD) – the prototype of these disorders - with pernicious anemia (PA), sometimes as a component of pancytopenia, is rarely described. Between 50 patients operated on immunologic hyperthyroidism in a 20 years period only one case related this uncommon combination.Case report: AB, a 46-year-old woman w...

Background: Parathyroid adenomas represent the most common anatomoclinical variety of hyperparathyroidism.Material and method: From our experience of 84 cases of hyperparathyroidism – 20 primary and 64 ‘renal’ (CKD-MBD) – 18 patients underwent surgery for solitary adenomas of these glands. Clinical data, laboratory and imaging test results, surgical procedures and outcome were comprehensively analysed.Results: W...

Background: The presence of striking cardiovascular manifestations was noted in the first descriptions of hyperthyroidism owing to Parry (1825) and Basedow (1840) in the famous Merseburger triad. Hyperthyroidism may either cause cardiac complication in individuals with a normal myocardium (genuine form of disorder) or complicate pre-existing cardiac troubles.Patients and methods: An homogenous series of 49 cardiothyreosis, 11 males and 38 females, aged 1...

Background: Concomitent occurrence of primary (PHPt) or renal (RHPt) hyperparathyroidism and papillary thyroid microcarcinoma (PTMc) is rarely described in literature.Patients and methods: Between 1986 and 2010 sixtythree subjects undewent operations for PHTp (n=20) or RHTp (n=43) in our clinic. In three cases (4.7%) a synchronous PTMc was intraoperatively discovered.Results: First case, female – 56 years old pre...

Background: The aim of this report is to describe a fortuitely discovered association between parathyromatosis and occult sclerosing papillary carcinoma of the thyroid.Case description: A 56-year-old woman presented with pyelic relapsed stone, bone pains and iPTH=348 ng but normal calcemia as manifestations of recurrent primary hyperparathyroidism after a right inferior parathyroid adenoma resection done elsewere 6 years ago Sonography showed a 5 mm hypo...

Background: Surgery which was until sixty years ago the only treatment available for Graves’ disease (Gd) is now the last recommended therapeutical option, the number of thyroidectomies (Tx) being in continous decrease. American physicians prefere radioiodine use while their European and Japanese colleagues like better long-term administration of antithyroid drugs.Patients and methods: A retrospective study carried out on 52 consecutive patients wit...

Background: Parathyroid carcinoma (PC) is a rare endocrine tumour, with difficult intraoperative recognition, histological diagnosis and imprevisible evolution. More unusual are the cases appearing at the patients with end-stage renal disease on maintenance hemodialysis (22 observations in medical literature).Case report: A 46 year-old man which suffered of chronic glomerulonephritis from 13 years, being on hemodialysis from three years, complains of ast...

Introduction: The significant increase in the average lifespan of the general population lead to a proportional enhancement in the prevalence of benign and malignant thyroid conditions and equally the number of surgeries for this pathology.Patients and method: In a personal series of 464 thyroid disorders undergoing surgery over two decades we recorded 51 patients (21.5%) aged over 65 years of which 11 (2.4%) having over 75 years. Demographic, clinical a...

Background: Chronic inflammatory processes of the thyroid represents an important proportion of the gland’s pathology but the majority of them must be treated by nonsurgical methods, thyroidectomy remaining circumstantially indicated.Patients and methods: In 14 cases (3%) from 464 operations for different thyroid lesions lesions we have encountered authentic inflammatory processes in nine cases of Hashimoto’s thyroiditis (two associated with pa...